Loek Brinkman

Electrocorticographic dissociation of alpha and beta rhythmic activity in the human sensorimotor system

Abstract:

This study uses electrocorticography in humans to assess how alpha- and beta-band rhythms modulate excitability of the sensorimotor cortex during psychophysically-controlled movement imagery. Both rhythms displayed effector-specific modulations, tracked spectral markers of action potentials in the local neuronal population, and showed spatially systematic phase relationships (traveling waves). Yet, alpha- and beta-band rhythms differed in their anatomical and functional properties, were weakly correlated, and traveled along opposite directions across the sensorimotor cortex. Increased alpha-band power in the somatosensory cortex ipsilateral to the selected arm was associated with spatially-unspecific inhibition. Decreased beta-band power over contralateral motor cortex was associated with a focal shift from relative inhibition to excitation. These observations indicate the relevance of both inhibition and disinhibition mechanisms for precise spatiotemporal coordination of movement-related neuronal populations, and illustrate how those mechanisms are implemented through the substantially different neurophysiological properties of sensorimotor alpha- and beta-band rhythms.

Authors:

  • Arjen Stolk

  • Loek Brinkman

  • Mariska J Vansteensel

  • Erik Aarnoutse

  • Frans SS Leijten

  • Chris H Dijkerman

  • Robert T Knight

  • Floris P de Lange

  • Ivan Toni

Date: 2019

DOI: https://doi.org/10.7554/eLife.48065

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