Aging decreases auditory event-related potentials to unexpected stimuli in humans


Authors:

  • Robert T. Knight

Date: 1987

PubMed: 3587487

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Abstract:

A P300 event-related potential (P3a) was recorded to unexpected, deviant auditory stimuli requiring no behavioral response. This brain potential underwent systematic latency prolongation and amplitude decrease with advancing age. The age-related changes paralleled those of the P300 (P3b) recorded in target detection tasks. These results provide physiological evidence of a decremented CNS response to unexpected stimuli with aging.