Howard Globus

P3-like potentials in rats

Authors:

  • Shuhei Yamaguchi

  • Howard Globus

  • Robert T. Knight

Date: 1992

PubMed: 7681756

View PDF

Abstract:

Auditory event-related potentials (ERPs) were recorded from the skull surface in unrestrained, unanesthetized rats. Infrequent deviant tones presented randomly within a sequence of repetitive tones enhanced a long-latency positive component peaking at 240 msec. This rodent ERP was comparable to the human P3a component in latency and sensitivity to stimulus probability. The rodent may provide a useful model for investigation of the neural sources of the P3.