Authors:
Lusha Zhu
Adrianna C. Jenkins
Eric Set
Robert T. Knight
Pearl H. Chiu
B.R. King-Casas
Ming Hsu
Date: 2014
DOI: 10.1038/nn.3798
Abstract:
Substantial correlational evidence suggests that prefrontal regions are critical to honest and dishonest behavior, but causal evidence specifying the nature of this involvement remains absent. We found that lesions of the human dorsolateral prefrontal cortex (DLPFC) decreased the effect of honesty concerns on behavior in economic games that pit honesty motives against self-interest, but did not affect decisions when honesty concerns were absent. These results point to a causal role for DLPFC in honest behavior.