Authors:
June Gruber
Julie N. Lemoine
Robert T. Knight
Allison G. Harvey
Date: 2007
PubMed: 17952718
Abstract:
PRIMARY OBJECTIVE: To determine the mood profile and sleep functioning of a patient with left anterior temporal region damage characterized by post-operative symptoms of mania. METHODS AND PROCEDURES: In a structured clinical assessment, the patient's mood status, psychiatric diagnosis and sleep functioning - sleep onset latency, total sleep time, wake after sleep onset - were assessed. The sleep-wake cycle and daily mood was measured for 11 consecutive days. RESULTS: The patient met diagnostic criteria for bipolar disorder (excluding the requirement that the disturbance must not be due to a medical disorder) and delayed sleep-phase syndrome. Across 11 days, the patient exhibited elevated positive, but not negative, mood. Correlational analyses indicated a possible association between mood and sleep disturbance. CONCLUSIONS: This pattern of findings implicates the temporal lobe in positive mood regulation and sleep-related impairments.