Authors:
Andrew P. Yonelinas
Neal E. A. Kroll
Ian G. Dobbins
Michele Lazzara
Robert T. Knight
Date: 1999
Abstract:
Aggleton & Brown argue that a hippocampal-anterior thalamic system supports the “recollection” of contextual information about previ- ous events, and that a separate perirhinal-medial dorsal thalamic system supports detection of stimulus “familiarity.” Although there is a growing body of human literature that is in agreement with these claims, when rec- ollection and familiarity have been examined in amnesics using the process dissociation or the remember/know procedures, the results do not seem to provide consistent support. We reexamine these studies and describe the results of an additional experiment using a receiver operating charac- teristic (ROC) technique. The results of the reanalysis and the ROC ex- periment are consistent with Aggleton & Brown’s proposal. Patients with damage to both regions exhibit severe deficits in recollection and smaller, but consistent, deficits in familiarity.