The Knight laboratory is a cognitive neuroscience research laboratory within the Helen Wills Neuroscience Institute and Department of Psychology at the University of California at Berkeley.
Neuropathology & Neuroscience
Agenesis of the corpus callosum in an infant
Agenesis of the corpus callosum in an adult
Chronic bilateral temporal damage from trauma. Note unilateral atrophy of the mammillary body due to loss of fornix input.
Chronic middle cerebral stroke
Posterior cerebral artery stroke
Chronic infarction. Entire distribution of the middle cerebral artery
Bacterial brain abcess in the depth of the frontal lobe
Neurocysticercosis cyst in the superior frontal gyrus. Note invaginated worm head in the cyst
Neurocysticercosis. Note multiple cysts
Knife-like atrophy of the frontal lobe in fronto-temporal dementia
Frontotemporal dementia: prominent lateral frontal atrophy
Frontotemporal dementia: prominent medial frontal atrophy
Glioblastoma in lateral frontal lobe
Thalamic glioblastoma
'Butterfly glioma' in the frontal lobe. Note tumor has spread through the corpus callosum
Multicystic glioblastoma centered in orbitofrontal cortex
Basal ganglia hemorrhage from hypertension
Pulvinar hemorrhage due to hypertension
Hemorrhagic stroke in the anterior cerebral artery involving medial prefrontal cortex
Hemorrhagic stroke in the middle cerebral artery involving middle and inferior frontal gyri
Hemorrhagic stroke posterior cerebral artery
Acute Wernicke-Korsakoff. Note petechial hemorrhages in the mammillary bodies and thalamus
Orbitofrontal meningioma
Medial frontal meningioma. Note extra-axial location
Massive orbitofrontal meningioma
Parasaggital meningioma
Orbitofrontal meningioma
Bilateral frontal leucotomy for treatment of psychiatric disorders. Note massive damage to white matter in frontal lobe
Focal cortical dysplasia in the lateral frontal lobe
Bullet track traversing bilateral frontal lobes
Huntington's Chorea
Chronic Herpes Simplex Encephalitis with Kluver-Bucy syndrome
Bullet through frontal lobe
Chronic bilateral temporal damage from trauma. Note unilateral atrophy of the mammillary body due to loss of fornix input
Temporal lobe contusions from traumatic brain injury
Temporal lobe contusions from traumatic brain injury
Massive frontal meningioma
Massive frontal meningioma
Massive frontal meningioma
Acute extensive hemorrhages in bilateral orbitofrontal cortex secondary to traumatic brain injury
Chronic extensive bilateral orbitofrontal damage to the orbitofrontal cortex from trauma. Note damage to both olfactory bulbs with resultant anosmia
Chronic unilateral orbitofrontal damage from trauma. Note damage to olfactory bulb on the side of tissue loss
Chronic orbitofrontal contusion
Szczepanski & Knight (2014). Neuron.